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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0303dc5b53f3c3ba2fedb89bb1fcc905a4a349187722ddd15d75ab241b771440' 
  AND token = 'iBJdPZLFR7d93OOsNU2wihU0vBByn5cVsM7zisoSeE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}