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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a6704f39350b7190108de1bdb99e547d99f5f0a46ad3f51e243656cad815044' 
  AND token = '8GnQG67bGMNRp1f7jsF36c69xs9UNtnP0gMqm1k7uIs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}