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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea171c3d62055e7dcca837f4fe2b97d6146cd0aab85a8508fe131b2ff292d47' 
  AND token = 'Md+a9ysEnZlZd395VRMIWtqYvYCYO8RJ+GRxc4v07Jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}