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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43d1f19ae4a17ade167d1e5b9f0bbfc78d32d02887f856ad62eabe67acad88a0' 
  AND token = '3/Xu/g+ELnZwekJ6021ya/6flu176cVZcOhjMj4tFeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}