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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b74210b81f9c3525546bf3a6b03695527d6644a952c471ffb65a1f0649647b14' 
  AND token = '3v2iQYVxoekGNug358pVA47OPPv77E9cgyEVbHeiAH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}