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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c65513beb30b678bc2359e36d97a26310c869c4699ffc0c32a99b24a0537c22' 
  AND token = 'TrrjKvihv+iC6aruimMQtUo0QnNor8XUFzq49cVMXv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}