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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea186ff24d443020b6a2271df04f1113465ed3603a7eafe67c87b78285158387' 
  AND token = 'yrLfeMGJmh60RgqLqx8ftmOP4XSA0u/LX3GU7x8hBZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}