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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd39642c375618533b950ca911463057a415916e4d23cc176745a784c42d6af59' 
  AND token = 'cgFKSiONF2yErK+QhSfKpgZ2FHenM/AMwp97Jg1HVpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}