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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a11c22c9e94d57a7d9e188bffba290cc93445ed911bea072a2aba431493a3879' 
  AND token = 'mBhh/Vr3p2DZ8umPdnVrYFYe7DMguhDpW9WNRUNzMn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}