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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99cc2476ac17a3dffeb1a3da96ca6892637a4a85498080c820031085105aba3c' 
  AND token = 'ElErXjMoggC38YAFy+auugzOmMENB2jL2Jxzq8XgTCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}