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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4481bf44eb16b4aa8fc3203342853690a40b793aeb60f458e8ebce56752de15' 
  AND token = 'UrKwm7Y/XyTc2UwRt6a6ncruY9KXE0+lInFMz1zNaqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}