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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b545e93be9b90978dd1f6fad0545ea707277278d4e04a57b4e226fe9d1bf8000' 
  AND token = 'p5IaBP8WoEOrlWsngd3itdoOVrdxR32AapN/cZTKGvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}