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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '745a07e3f3307708014cd9b9483e8a625e6c3081e9b5933e05d723282b06148e' 
  AND token = 'jrFxPxFXBsynGJ5UM2yjtlaFgzmDAILmUGxU5YUdlM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}