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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a68007cb0c568a2342caf9ea302fe64d7a3255e43e251e203eba8c85472c9d7' 
  AND token = 'o+PJ8QjBq4tx0TnnIvJ2N2I1Ax2q0wkB6IH9ZlTRayY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}