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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28edb50de5153bb7bc37ad82f1b1bacc2d4d5d53472d5833f27bea5988351b9f' 
  AND token = 'jOvrgC1lVAUGrSc8JLDtVUPbDSeMbG7GVJ4dBu8z8c4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}