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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7df92a18b311b6be3e431b90e72921ad3def43ba80fc0e56172b1d4aa29f308' 
  AND token = 'gr78JP/2SXzAMKsrJFeJkGkv+MhTXfsj8H3FUuEvuxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}