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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c260c4eb7678ac314390023db9b92b1cf3ff39bb68d1331d06a0dce6ac87249' 
  AND token = 'cXYZj05ejJLAISHSwLqMZMx8JQUIXjbcBpCbu5mS9b8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}