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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5258c253f3d92c4f83bfe16ff7892d7662ff2e120d4be206aed0cac4d49e8c' 
  AND token = 'giaT54bgcGkPq2n2tbi3DlSNk9vXSoeXddtVc7rwyPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}