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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2be67bc0556ab6a61d0ecb6cf59a57eed19d6b442d7df5b2e4a3d1b16aa07c14' 
  AND token = 'IsDLQj4tGUjTmbnFgjO4w7GdHlhu0qS6fsnTcKSI3dE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}