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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51003e7c278852b8a6c3512f4bc5208337bc6dfe6ba520e470f208f084417c1f' 
  AND token = 'r9VG4LQk3c4Fw/q1FpOKqWWMv6U2HxPTZEPRfeexiEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}