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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4fc34ad5c562d16111a436df1c4810afc009bbf0bdf5254bc92443b76948b6' 
  AND token = '6Xl7Ytd80g+ayGIc/0A1mFwmpXLtO8j5B8aArBi7T8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}