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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a28609a79d6fb0cf1f823f9bca5250fb840c46efe9869479506a0f7644dfa79' 
  AND token = 'r37aLX3at4kd6UcUgTkQcUxalwZA7jD1xfg29IvHlYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}