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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ed507d224b35c62a7ffc14b96a9f7db93b497814c6faf75e54e3f84031fe3ce' 
  AND token = 'cmkU+IwPuJKQq2BfbbhNsSmlz2blopJG3UdDo7yRMIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}