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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5adffd80bca30aa21f64024eee2a20e8d9ddcd90aad7fc0123fa71ef5f930000' 
  AND token = '/2I5JkFFx7vZHzPM42ZppgaSbESljyYBenQDm1B1ujQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}