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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '693d33c399389ca2c1bbf12c069ee06d87b2780311b198fe07ef19b03cbd8d1f' 
  AND token = 'Zl3S4xZeV6F1te1d8YM+7V/BHsCXyNt2eDQmMibNik8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}