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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f822a1a819c9e683ea2813d379d9a5f04d9c12c74ca47f49cb3a7fd2477ad26' 
  AND token = 'SRZxxly+BUsBZrbUAgPxRceeccMPmZeO2KcKXWw0vcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}