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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd016c6a2efb3af9dabbc7cc98efa18f48e5e6ef01cadaedb3baf9c7d5a0053' 
  AND token = 'e6clMChl9TDrZ9liACwCRqrydk7za0shznYwYdeDdqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}