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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a72169b56b37dbf132e72aeeed32cdbdc83ee6cfe04c4d194b057cf58f4461d' 
  AND token = 'Hy2X2ArU/x0w1hJXoGEwtHxlCrfrDElW31Suv069gi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}