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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '861e621d754bf106635989bbede48980a80c9ec70932c2424b08947cbd473cea' 
  AND token = 'v2o0aIGdCXQ9a8h0jg45lz+oxJ1JxyAo+VJMThMz4rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}