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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '769232a7db8004492bb50306b2dc99f6adcae3e48fd32109e05d358a52671cd2' 
  AND token = 'ciQXNipLRuyyYOqusC/5TQhpyJYGt1yrPq15t0ywn3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}