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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ec23417bae5610c75a0e82321e88358ae6fada7c689bdfae64b83b32b50e00d' 
  AND token = 'MlpnxG5dLYKDmVn+EH8mfvDxYEhnviDSdOiECHP3AJI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}