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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a88989aff8b0209697df916a3b1da93924a7b553bbcdf50f1c5bffb1cb5f42a3' 
  AND token = 'cfaonCaB5S9s97ZOOiORwSJ/lUXzhvmy8Y8YvwdVRXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}