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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d45e64fabf7f17c12213cb0b68be5a5cf70ad3114aa8213b1a8ecb6d77c9789' 
  AND token = '0exIRQArKO5p40ymkgh84ok1OnHpvRGlTCC6LO1BqVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}