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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0270845b0c4f1733edb72229b1c32b54189c3a21aa15662841e297b13342a6ae' 
  AND token = '1SEcSNFAtKuS3YUmtHzq6WCdsxj9OrkJlnUrdtVplbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}