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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1457f758b1d486b296fb0883c8866cad162a5df4dcace5e4a608339bb700ae9' 
  AND token = 'HWyPIxR/t1fDQvGZeknlBK+RQMP5tYm42KuvcOo2c6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}