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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1f0beb1b32c02183eee8ae9d605410041c925111df36852f57d7c9892d1c3d1' 
  AND token = '+tVUrN0lZeR/UkMg8JyTHXqoiew4wGjAl5Ei9h6usAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}