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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8300d7a472a5068b63267d110c2acefb51cb35b62831c09f50fae254a6edd458' 
  AND token = 'H5rVkJY87j2rkWctHcjXd73algqvDumD7wvqKsxgWFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}