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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e48aecb32b3b1f44b80f6115d1ffd5538e8c4748afd4a6c8163e3a0d616fc1d' 
  AND token = 'imc8VeJnKTSnurCqgKwcf2NVv2UoXpLJF4BedSDACQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}