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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2b3f2528b91e0abecd69bb308a29df576f81ed87e7849cda59c3b37853471a' 
  AND token = '3sq4HHZDop3scjhbF6QpsF2DuqTWf4tABC2ZcaLcidE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}