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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45eadf3003b1039db4830fae0c74c29b99484128d71ff287b65cbc03c9f86bfa' 
  AND token = 'oFbxA6LCp1hwDwil5K5gNcGLpMESaB3+iHBm5S+ln/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}