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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab965e208597a95c91e3f703c4f2229018c58f805a39d9536fb391e1894f7b6b' 
  AND token = 'xXYyDH5wmaMjXnQF3l6uibtk3pM7YdndacJMXlCjyRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}