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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c49c6f61f682b1dd83cde4657be09369c428b253b1cbc0b4a0ff68c8cb7ed4' 
  AND token = 'z0urvgbjMSq+efpavmp8BN9YDfnhNb9x31p1HilbJgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}