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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39120020280bbb03cbcd83d15b530dc47ce603afac1aba84186578f90d2f094d' 
  AND token = 'ymUQ9FhgA+UR/33sWwbt4HmAVNNHpH3Zfvn6R1oSJ2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}