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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35fe099ca505f3d78465fefb70d05bb09dcb89c4c6db35ef30185dda1282129d' 
  AND token = '5YMvNKYDzjLN+xr4iAIAueEkIz0qoNXZIXz/3D+4LAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}