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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc4718d71dd4c77dd73cd06dbd2b039031c4661851d40014398f2f8b9d35576' 
  AND token = 'hR7/y4lxm6md/cQ5r8pqUYrfGBdKuNOTulNj4ScA+R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}