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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa51aabe3205cd80444abec3fddc9f8b0e218a759fab7f69e89aa0a937506729' 
  AND token = 'GIX35uxNzjQ6uG6QjsG5oJVF8WQ0Qb++fOkCcpJDru4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}