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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a5f00ec2a3f6e8966ba183d4cb7c092c3fec910fd2f8ea97010e899278a20b6' 
  AND token = '72YEMCkw064bLDnhKRD6R0fomAP/OuCouLUCprhC/bE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}