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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2627735e4efa78c3526b599901111b5818e01c4c0a44b968808d6b656a9e4973' 
  AND token = 'rzd91IcV3mciew431euxjWNf1zdWmFR3eFlBfEliyr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}