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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd500278b34e61c427f160b49112485aafa35441417c33e410bc24688ef690c15' 
  AND token = '19ZcmfMf8z5bPeD32HiFiZLx1muvnpypzi4P7iPezWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}