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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8e3efa95b4f83bd14143fbf1c004ea5d3bb9881bea064daff6da9110bf6eeae' 
  AND token = 'T4soMFe+SWJTy0CZikza31UZ7xSwymbz4NTabg41+ZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}